A selection of recommended internet resources aimed at ELSI practitioners, students, and any interested members of the public to help understand the science behind the latest health care developments
- Educational Resources
- Open Access Publications
- Subscriber Only Publications
DNA from the beginning :An Animated Primer on the Basics of DNA, Genes and Hereditary
Cold Spring Harbour Lab
Learn Genetics: Genetic Science Learning Centre
University of Utah
Personal Genome Project Study Guide
Useful Resources for Understanding Key Scientific Developments in Genomics
Open Access Articles
Janssens ACJW, Duijn CMv. Genome-based prediction of common diseases: advances and prospects. Human Molecular Genetics. 2008;17(Review 2):R166-R172.
Tian C, Gregersen PK, Seldin MF. Accounting for ancestry: population substructure and genome-wide association studies. Human Molecular Genetics. October 15, 2008 2008;17(R2):R143-150.
McCarroll SA. Extending genome-wide association studies to copy-number variation. Human Molecular Genetics. October 15, 2008 2008:ddn282.
McCarthy MI, Hirschhorn JN. Genome-wide association studies: past, present and future. Human Molecular Genetics. October 15, 2008 2008;17(2):ddn298.
McCarthy MI, Hirschhorn JN. Genome-wide association studies: potential next steps on a genetic journey. Human Molecular Genetics. 2008;17(Review 2):R156-R165.
Attia J, Ioannidis JPA, Thakkinstian A, et al. How to use an article about genetic association B: Are the results of the study valid? Journal of the American Medical Association. 2009;301(2):191-197.
Attia J, Ioannidis JPA, Thakkinstian A, et al. How to use an article about genetic association A: Background concepts. Journal of the American Medical Association. 2009;301(1):74-81.
Subscriber Access Only Articles
Phillips PC. Epistasis - the essential role of gene interactions in the structure and evolution of genetic systems. Nature Reviews Genetics. 2008;9:855-867.
Visscher PM, Hill WG, Wray NR. Heritability in the genomics era - concepts and misconceptions. Nature Reviews Genetics. 2008;9:255- 266.
Hurst LD. Genetics and the understanding of selection. Nature Reviews Genetics. 2009;10(2):83-93.
McCarthy MI, Abecasis GR, Cardon LR, et al. Genome-wide assocation studies for complex traits: consensus, uncertainties, and challenge. Nature Reviews Genetics. 2008;9:356-369.
Cordell HJ. Detecting gene-gene interactions that underlie human diseases. Nat Rev Genet. 2009;10(6):392-404.
Stephens M, Balding DJ. Bayesian statistical methods for genetic association studies. Nat Rev Genet. 2009;10(10):681-690.
Plomin R, Haworth CMA, Davis OSP. Common disorders are quantitative traits. Nat Rev Genet. 2009;10(12):872-878.
Ioannidis JPA, Thomas G, Daly MJ. Validating, augmenting and refining genome-wide association signals. Nature Reviews Genetics. 2009;10:318-329.
Orr HA. Fitness and its role in evolutionary genetics. Nat Rev Genet. 2009;10(8):531-539.
Holsinger KE, Weir BS. Genetics in geographically structured populations: defining, estimating and interpreting FST. Nat Rev Genet. 2009;10(9):639-650.
Charlesworth D, Willis JH. The genetics of inbreeding depression. Nat Rev Genet. 2009;10(11):783-796.
Charlesworth B. Fundamental concepts in genetics: Effective population size and patterns of molecular evolution and variation. Nat Rev Genet. 2009;10(3):195-205.
Burton PR, Tobin MD, Hopper JL. Key concepts in genetic epidemiology. The Lancet. 2005;360(September 10 2005):941-951.
Teare MD, Barrett JH. Genetic linkage studies. The Lancet. 2005;366(September 17 2005):1036-1044.
Cordell H, Clayton DG. Genetic association studies. The Lancet. 2005;366(September 24 2005):1121-1131.
Palmer LJ, Cardon LR. Shaking the tree: mapping complex disease genes with linkage disequilibrium. The Lancet. 2005;366(October 1 2005):1223-1234.
Hattersley AT, McCarthy MI. What makes a good genetic association study? The Lancet. 2005;366(October 8 2005):1315- 1323.
Hopper JL, Bishop DT, Easton DF. Population-based family studies in genetic epidemiology. The Lancet. 2005;366(9494):1397-1406.
Smith GD, Ebrahim S, Lewis S, Hansell AL, Palmer LJ, Burton PR. Genetic epidemiology and public health: hope, hype, and future prospects. The Lancet. 2005;366(October 22):1484-1498.